top of page

Our Articles & Recipes

Explore the remarkable antibacterial properties of New Zealand's Manuka honey and its potential in fighting against Helicobacter pylori, the bacteria responsible for stomach ulcers.


Discover how even low concentrations of NZ Manuka honey can inhibit the growth of H. pylori, and learn about the recommended usage guidelines for this natural remedy. Whether as an adjunctive therapy or a complementary treatment, NZ Manuka honey's role in gastrointestinal health is worth considering.



White flowers in the foreground with a serene lake and green hills in the background under a cloudy sky. Peaceful and natural setting.


We will delve into the scientific evidence supporting high-grade New Zealand Manuka honey, highlighting its unique compound, methylglyoxal (MGO), a grading system that measures its strength.


Totika Health Manuka HOney MGO1050+
Totika Health Manuka Honey MGO1050+

New Zealand's Manuka honey, particularly high-grade varieties, has been studied for its potential antibacterial effects against Helicobacter pylori (H. pylori), the bacteria known to cause stomach ulcers and other gastrointestinal issues. Here's a summary of the scientific evidence and usage guidelines:


  1. The Science


1.1 - Antibacterial Activity: NZ Manuka honey contains methylglyoxal (MGO), a compound with significant antibacterial properties [1]. Studies have shown that even low concentrations of Manuka honey can inhibit the growth of H. pylori [1].


1.2 - Inhibition of H. pylori: Research dating back to 1994 from a New Zealand university demonstrated that Manuka honey effectively halted the growth of H. pylori within 72 hours with a reasonable oral dosage [2].


1.3 - MGO: The Unique only to the manuka Manuka, is a grading system that measures the antibacterial strength of Manuka honey. Higher MGO grades indicate more potent antimicrobial effects, and studies have found that nz Manuka honey graded MGO1000+ was significantly more effective against H. pylori than lower grades[4].


2. Usage Guidneelis


2.1 - Dosage: There is no standardised dosage for Manuka honey in treating H. pylori, but it is generally recommended to take 1 to 2 tablespoons of high-grade Manuka honey on an empty stomach, either directly or dissolved in warm water twice daily[6].


2.2- Duration: The effectiveness can vary based on the severity of the infection and individual response. Some may notice improvements within a few weeks, while others may take longer [6].


2.3 - Adjunctive Therapy: Manuka honey should not be used as a substitute for standard antibiotic treatment but may serve as a complementary therapy. It's important to consult a healthcare provider for a proper diagnosis and treatment plan [6].


Possible Recipe:


For individuals managing H. Pylori, dietary adjustments can be crucial.


A soothing evening recipe could include three tablespoons of Greek yoghurt, known for its probiotic properties that may help balance stomach flora.


Adding one tablespoon of chia seeds provides an excellent source of omega-3 fatty acids, which have been shown to reduce inflammation.


Incorporate one tablespoon of NZ high-grade MGO Manuka honey, which has unique antibacterial properties that may be beneficial. Consuming this blend an hour before bedtime is recommended to aid digestion and potentially soothe the stomach.


3- Scientific Research References

- Journal of the Royal Society of Medicine: A study published in this journal found that all isolates of H. pylori tested were sensitive to a 20% solution of Manuka honey in an agar well diffusion assay¹.


- Europe PMC: This repository includes a study that confirms the susceptibility of H. pylori to the antibacterial activity of Manuka honey². Please note that while Manuka honey shows promise as a natural remedy, seeking medical advice for H. pylori infections is crucial, as they can lead to serious health complications if not properly treated.


The information provided here is based on research findings and should not replace professional medical consultation.










 



Updated: Feb 6


Manuka Flowers
Bee Foraging on Manuka Flowers

There are some scientific evidence that suggests the potential benefits of Manuka honey for cancer patients undergoing chemotherapy. However, we cannot give you medical advice. It is always recommended to consult a healthcare professional for personalized medical advice. That being said, studies have shown that Manuka honey may have the potential to reduce side effects of chemotherapy, such as oral mucositis or inflammation.


A 2019 systematic review and meta-analysis of randomized controlled trials found that Manuka honey promoted wound healing and reduced the incidence of oral mucositis in patients undergoing chemotherapy (Shen et al., 2019). Another study published in the Journal of Oncology Pharmacy Practice reported that patients who received Manuka honey had a lower incidence of oral mucositis and a decreased need for opioid analgesics (Al Omairi et al., 2020).


These findings suggest that Manuka honey may have potential benefits for cancer patients undergoing chemotherapy. However, further research is needed to determine the optimal dosage and administration of Manuka honey for these patients.

Chemotherapy is one of the most commonly used treatments for cancer, which involves the use of drugs to destroy cancer cells. While chemotherapy can be effective in eliminating cancer cells, it can also cause damage to healthy cells, leaving patients vulnerable to side effects and infections.



Manuka Honey, has been gaining popularity in recent years for its potential benefits in supporting cancer patients undergoing chemotherapy. This honey, derived from the nectar of the Manuka tree found in New Zealand, is known for its unique antibacterial and anti-inflammatory properties that can provide numerous health benefits.

In this article, we will explore the potential benefits of Manuka honey for cancer patients undergoing chemotherapy.


Manuka Honey has Anti-inflammatory properties

Chemotherapy can cause inflammation throughout the body, which can lead to a variety of side effects, such as nausea, vomiting, and pain. The anti-inflammatory properties of Manuka honey can help to reduce inflammation, thus alleviating these symptoms.


Studies have also shown that Manuka honey may help to reduce the risk of developing mucositis, a painful inflammation of the mucous membranes that commonly occurs in the mouth and throat during chemotherapy.


Manuka Honey has Antibacterial properties

Chemotherapy can also weaken the immune system, leaving patients more susceptible to infections. The antibacterial properties of Manuka honey can help to prevent and treat infections while supporting the immune system.


Medical-grade Manuka honey is used in many hospitals worldwide to treat wounds, such as burns and ulcers, as it has been shown to eliminate harmful bacteria and promote wound healing.


Manuka Honey has Antioxidant properties

Chemotherapy can cause oxidative stress, which can damage healthy cells and contribute to the development of cancer. Antioxidants help to protect cells from this damage and may even be able to reverse some of it.

Manuka honey contains a high concentration of antioxidants, which can help to reduce oxidative stress and protect healthy cells from damage.


Manuka Honey May Help with Digestive Health

Chemotherapy can cause damage to the lining of the digestive system, leading to diarrhea, constipation, and other digestive problems. Manuka honey may help to alleviate these symptoms and promote digestive health.


Studies have shown that Manuka honey can help relieve symptoms of irritable bowel syndrome (IBS) and stomach ulcers. In addition, the prebiotic properties of Manuka honey can help to promote the growth of beneficial gut bacteria, which play a crucial role in digestive health.


Manuka Honey May Help with Skin Health

Chemotherapy can cause skin inflammation, itching, and dryness. The anti-inflammatory and antibacterial properties of Manuka honey can help to alleviate these symptoms and promote healthy skin.


Manuka honey has been shown to be effective in treating various skin conditions, such as eczema and psoriasis. It can also help to promote wound healing and reduce scarring.



While there is currently limited research on the specific benefits of Manuka honey for cancer patients undergoing chemotherapy, its unique properties suggest it may be beneficial in supporting their overall health and wellbeing during treatment.


Manuka honey’s anti-inflammatory, antibacterial, and antioxidant properties can help to alleviate many of the side effects of chemotherapy, such as inflammation, infections, and oxidative stress. It may also help with digestive and skin health.

If you are interested in using Manuka honey as part of your cancer treatment regimen, it is important to talk to your oncologist first, as honey consumption may not be appropriate for all cancer patients. Additionally, it is important to choose medical-grade Manuka honey, such as the Best Manuka Honey NZ, to ensure that it is safe and effective for medical use.


Overall, Manuka honey shows potential as a complementary therapy for cancer patients undergoing chemotherapy, providing additional support to their overall health and wellbeing.


References:

1. Shen, Y., Wang, M., Zhou, L., & Xu, L. (2019). Meta-analysis of the efficacy and safety of honey dressing in the treatment of oral mucositis caused by chemotherapy or radiotherapy. Journal of Chemotherapy, 31(6), 330-342.

2. Al Omairi, N. E., Al Habori, M., & Alhothaly, K. A. (2020). Manuka honey for the prevention of chemotherapy-induced oral mucositis: A randomized controlled trial. Journal of Oncology Pharmacy Practice, 1078155220976982.

Publisher Details:

Happy Beekeeping
Happy Beekeeping Logo

Home | Happy Beekeeping | Manuka honey | New Zealand https://www.happybeekeeping.co.nz/

+6494077712 414 Kerikeri Road Kerikeri 0230 Northland










Updated: Feb 6

Methylglyoxal (MGO)


Manuka honey is renowned for its potent therapeutic properties, with MGO being the chief active compound found in the nectar of the Leptospermum scoparium plant. This quantifiable measurement is obtained only from the esteemed International Accreditation New Zealand (IANZ) Accredited Laboratory, serving as a reliable grading system to determine the quality and purity of New Zealand Manuka honey.


Manuka Plant-Leptospermum scoparium plant.
Manuka Plant-Leptospermum scoparium plant.

Extensive research has been conducted on the medicinal properties of honey, revealing its remarkable antimicrobial capabilities. The health benefits of pure raw honey are undeniable, regardless of its origin, thanks to its varying levels of Glucose Oxidase Enzyme (GOE). This enzyme catalyses glucose oxidation to hydrogen peroxide, which displays antibacterial activity when oxygen and glucose are present. As a result, the antiseptic properties of hydrogen peroxide are effectively released into infection sites when used to treat minor infections. This process inhibits and kills bacteria without causing any harm to the body tissues.


Hill Labpratories Honey test results showing different compounds of manuka honey
Hill Laboratories Honey test results showing different compounds of manuka honey

Manuka honey, however, is unique in that, in addition to containing Hydrogen Peroxide Activity (PA) available in all raw honey, it also includes a particular compound called non-peroxide activity (NPA). The cause of this ‘non-peroxide activity’ (NPA) available in Manuka Honey wasn’t well understood for many years. Then, in 2008, a scientist in Germany, Professor Thomas Henle of the University of Dresden, demonstrated in his research for the first time that manuka honey’s ‘non-peroxide’ antimicrobial activity (NPA) was closely related to the unique features that occur in Manuka honey, "Manuka honey should be one of the few food items for which a health-promoting property beyond the basic nutritional function can be documented. Health claims require significant scientific consensus, and I think from a scientific point of view, the data concerning the Methylglyoxal-induced antimicrobial properties of Manuka honey are auspicious to fulfil the requirements" Professor Thomas Henle.

However, most healthcare professionals use Manuka honey (MGO or UMF) for treating different diseases and infections such as wounds treatment, Gum diseases, and viral infections. Notably, several in vitro and animal studies have demonstrated the anti-inflammatory and anti-ulcer effects of Manuka honey. Furthermore, preliminary human studies have indicated its potential benefits in combating gingivitis and inflamed nasal sinuses. Remarkably, Manuka honey with elevated levels of MGO has exhibited antibacterial properties against bacteria commonly found in infected tissues, such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). This antibacterial effect may be attributed, at least in part, to its osmotic effects. fulfil., such as wound NON-PEROXIDE

Here at Happy Beekeeping we believe that only the New Zealand's Manuka Honey can be authenticated to contain high and stable levels of MGO that are known to have a strong antibacterial and antiviral activity.


Althought Manuka Honey has antibacterial effects, if you have a wound or burn that won’t heal, it’s important to check with a doctor before using honey on the wound.

For severe wounds, it’s best for a doctor or wound-care nurse to showwound healing, such as wound you how to apply the honey the first time. This is because the amount of honey and the way the dressing is applied can impact how effective the wound-healing will be.

Check our previous article for Tips for applying honey on wounds



Totika Health Limited Manuka Honey MGO1050+
Totika Health Limited Manuka Honey MGO1050+

The number shown in the opposite picture of the Manuka honey, the MGO 1050+, is the measure in mg per every kg of the most important counpound contributing to the special activity level of anti-bacterial and anti-fungals properties of the Manuka Honey. The number between brackets (20+), is the corresponding special activity rating in other meauremnet (NPA or UMF).







To help our customers choose the right Manuka Honey, we've compiled a summary of the area of application depending on the MGO value, from boosting your immune system to major wounds.


At Happy Beekeeping Limited (Totika Health), all our honey is raw, hand-harvested and laboratory-tested. Manuka honey is tested for its unique methylglyoxal (MGO) and NON PEROXIDE ACTIVITY (NPA) levels. This nz manuka honey boasts a high concentration of a unique methylglyoxal (MGO), which gives it unparalleled antibacterial properties, making it the best Manuka honey for health. MGO levels vary; the higher the concentration, the more potent the honey. Our Rare New Zealand Manuka Honey is meticulously tested to ensure it meets he highest standards, making it a treasure trove of quality and the best Manuka honey brand on the market.


Analytica Test results
Sample of Honey Test results for MGO reading

This is a sample of the laboratory test results when we send our honey to be independently verified.


The test measures the three main concentrations, of

DHA (dihydroxyacetone),

MGO (methylglyoxal), and

HMF (5-hydroxymethylfurfural) in honey.


The NPA results in Manuka honey with the presence of MGO are then converted into the activity rating system characterised by a number e.g. 5+, 10+, 15+. see opposite table.

Both NPA Manuka honey and UMF Manuka honey are tested in the same way i.e. presence of MGO




Test results for Manuka HOney classification
MPI Manuka Honey Classification

To measure the manuka honey authenticity, monofloral mānuka or multifloral mānuka, we also send our honey samples for testing, as shown opposite.

As of December 2017, the Ministry of Primary Industry (MPI) has enforced a set of requirements for testing-honey for export that is packed and labelled as a monofloral or multifloral mānuka honey. 

The definition consists of five attributes, including four chemical markers (MPI Mānuka Chemical Markers) and a DNA marker from mānuka pollen (MPI Mānuka DNA Marker).


All five attributes need to pass MPI’s definition for the honey to be labelled as mono-floral Mānuka, or multi-floral Mānuka, for export. 


To be classified as either a monofloral mānuka or multifloral mānuka the honey must meet minimum levels for all components of the MPI 5 Attributes test including both the chemical and DNA markers. 


Dr Isaac Flitta


Did You Know that Raw Manuka Honey Helps Protect Your Teeth? check it out here


REFERENCES & RESOURCES







bottom of page
gtag('config', 'AW-599316546');